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Melasma is a skin problem that is caused due to the overproduction of melanin and causes brown or grayish patches. It is caused by a range of factors including hormonal changes, genetics and sun exposure. Nevertheless, current treatments coupled with proper sun protection can effectively reduce the darkness of the patches, as well as improve the overall skin appearance in Islamabad. 

What Is Melasma? 

Melasma is a chronic dermatosis characterized by symmetrical tan or brownish patches, typically on the cheeks, forehead, nose, upper lip and chin. The disease is caused by an overactive melanocyte that is triggered by visible light, hormonal imbalance, UV light or genes. Melasma is not a life-threatening condition, but it can have a negative impact on a person’s quality of life and self-confidence. 

Is Melasma the Same as Hyperpigmentation?

No, a darkening of the skin resulting from an increase in melanin is called hyperpigmentation. The dark patches on the skin, characterized by unique causes and appearance, are known as melasma. There are other types of hyper pigmentation like sunspots, age spots and post-inflammatory hyper pigmentation which need different methods of treatment. 

Is Melasma a Medical Disease?

Melasma is not regarded as a serious condition of skin; it is just a skin disease. Does not cause skin cancers or other problems, but it is frequently a persistent or recurring condition. This requires continuous treatment and protection of the skin from the sun. 

What Causes Melasma? 

The main causes of melanism are hyperactive melanocytes and overproduction of melanin. This is a condition that seems to occur for a variety of reasons, not just one. 

Sun Exposure

Ultraviolet radiation, which is a part of sunlight, is the most potent activator of melanocytes. 

Visible Light

Another reason why melasma occurs is exposure to blue wavelengths of visible light. This kind of light is more harmful to the skin, particularly darker skin. 

Hormonal Changes

This disease can be triggered by hormonal changes, such as taking hormone replacement therapy, contraceptive pills containing hormones, or pregnancy. 

Genetics

A tendency to develop the disease because it runs in the family is also a risk factor. 

Heat

Excessive heat can trigger melanocytes, thus making it more likely to develop melasma. 

Cosmetics and Skin Irritation

Certain cosmetics and skin care products cause skin irritation, thereby worsening the severity of melasma. 

Medications

Certain medications that are sensitive to sunlight may lead to melasma. 

Who Is More Likely to Develop Melasma?

Women

Melasma occurs much more often in women rather than men due to the powerful influence of hormones. 

Pregnant Patients

The “mask of pregnancy” is the common term for melasma because it frequently occurs during the period of conception because of hormonal variations. 

People With Fitzpatrick Skin Types III–VI

The tendency to melasma is higher in people who have moderately dark and very dark skin tones. 

People With a Family History

Having a familiar history of melasma greatly increases the chances of developing the skin condition. 

People Living in Sunny Climates

Residents in the sun-battered West Virginia will be exposed to more UV radiation, which can stimulate melanogenesis. 

People Using Hormonal Treatments

Several hormone treatments can make existing melasma or trigger new melasma. Contraceptives and hormone replacement therapies are examples of such treatments. 

Where Does Melasma Appear?

  • Cheeks
  • Forehead
  • Upper Lip
  • Nose
  • Chin
  • Jawline
  • Neck and Forearms

Melasma Patterns 

There are three types of melasma centrofacial melasma, malar melasma, and mandibular melasma—these are determined by the location of the dark area. Depending on the location and appearance of the pigmented areas, the dermatologist can ascertain the best treatment 

Centrofacial Pattern

This is the most common type of melasma and is found on the forehead, nose, upper lip, cheeks and chin.

Malar Pattern

It is of this type when it involves the middle parts of the cheeks, and it is extended to the bridge of the nose. It also darkens with sunlight. 

Mandibular Pattern

More uncommon, melasma to the lower face and jaw line. There is potential confusion with other skin diseases and this type should be evaluated by a dermatologist. 

Types of Melasma by Pigment Depth 

The depth of the deposit of the excess melanin determines the type of melasma. Classification is important because the degree of melanin involvement in the layers of skin determines the type of treatment, the effectiveness of the treatment, and the risk of recurrence. The clinical examination and examination with the use of special tools such as a Wood lamp can help a dermatologist determine what type of melasma a person has.

Epidermal Melasma

The epidermis is the uppermost layer of the skin and in epidermal melasma, the excess deposit of melanin occurs in the epidermis. In this type, there are brownish patches and it is more likely to respond to good treatment like professional peels and topical treatments. 

Dermal Melasma

Due to the deeper penetration of melanin into the dermis, this type of melasma is more challenging to treat and usually has a gray or blue coloration. 

Mixed Melasma

This is the most frequently occurring form of melasma, which is made up of a combination of dermal pigmentation and epidermal pigmentation. Topical and in-clinic treatments are recommended for combination melasma.

Indeterminate Melasma

In some cases the pigmentation may not be clearly demarcated, creating some diagnostic and therapeutic difficulties which require an individual evaluation and treatment plan. 

How Is Melasma Diagnosed? 

The most frequent way of diagnosing melasma is by visual inspection carried out by a trained dermatologist. The primary goals of the exam are to determine what kind of pigmentation pattern it is, and to rule out other conditions that could cause facial darkening. 

Medical History

These are the factors to be taken into account: formation of pigmentation, sunlight exposure, pregnancy, use of hormone-based drugs, genetic susceptibility and previous dermatological treatments. 

Clinical Examination

An inspection will be useful to help identify the position, colour and symmetry of the spots. This skin condition is normally seen on sun exposed areas of the face. 

Wood’s Lamp Examination

This test is done to determine if the melanin pigment has built up in the uppermost layer of skin or deeper layer. 

Dermoscopy

The examination makes a more accurate diagnosis of vascular changes and distribution of pigment in the skin. 

Is a Biopsy Required?

A biopsy is not necessary but it can be performed to confirm the diagnosis. 

Melasma Treatment Options 

The goal in treating melasma is to even out the appearance of the skin, stop it from happening again and reduce the excess pigmentation. This is a condition that cannot be cured but can be best treated with a mixture of professional treatment, skin care and sun protection. The best treatment will be decided by a dermatologist based on the severity of the pigmentation, the depth of it, and the type of skin. 

Broad-Spectrum Sunscreen

Sunscreen use is the most crucial part of the treatment of melasma. Exposure to UV radiation can trigger melanogenesis, which can be prevented by wearing a broad spectrum (UVA/UVB) sun cream with SPF 30 or higher. Iron oxide in the sunscreen can help protect against visible light, which can be particularly important for those with darker complexions. 

Hydroquinone

Probably, the most popular medication for reducing melanin production is hydroquinone. This substance works by inhibiting the activity of tyrosinase which decreases the production of melanin in melanocytes. Due to its possible harmful effects it may be given by a medical professional. 

Triple-Combination Cream

The triple combination of hydroquinone, a retinoid, and a mild corticosteroid is used in order to reduce inflammation, cause dermatosis regression and prevent pigment synthesis. It’s recommended to use for short-term treatment of moderate or severe melasma. 

Azelaic Acid

The mild topical agent which can be used for the suppression of irregular pigment production and reduction of irritation is Azelaic acid. It is suggested for the treatment of sensitive skin and, if approved by a doctor, it is possible to use Azelaic acid during pregnancy. 

Retinoids

Retinoids have been shown to improve the action of other topical medications to help with the turnover of skin cells, which leads to quicker shedding of any pigmented cells. This medication should be used with caution as it can have side effects such as dry, irritated, and red skin. 

Cysteamine

Cysteamine is an anti-oxidant and depigmenting agent. The drug can be used for people who have a melasma diagnosis and have been unresponsive to other treatment options. It is able to block the synthesis of melanin, which decreases the amount of melanocytes. 

Kojic Acid and Arbutin

Plant origin acids such as kojic acid and arbutin are capable of inhibiting melanin production. They can also be utilized to peel back the grayish pigmentation layer and are that’s why found in numerous glowing serums. 

Tranexamic Acid

A new treatment for melasma is tranexamic acid. This acid is an inhibitor for the synthesis process of melanin. The method of using this substance is under consideration – both oral and topical application are possible. But, the use of oral administration should be avoided without consulting a dermatologist because there are certain risks involved. 

Niacinamide and Vitamin C

Vitamin C, a potent antioxidant, can help eliminate spots and even skin tone. Niacinamide decreases the transfer of pigment to the skin cells. The two ingredients are beneficial for the skin in many ways. 

Pregnancy-Related Melasma

Pregnancy associated melanosis will start to subside when the hormones do not come from the female body and levels even out. The three key principles of treatment are: photoprotection, gentle topical treatment and safe skin care.

Chemical Peels for Melasma

A chemical superficial peel will help to eliminate hyper pigmentation and peel away the damaged outermost layer of skin. But these should be carried out only by professionals to prevent unwanted effects which can worsen the melasma. 

Microneedling for Melasma

Micro injuries caused by microneedling stimulate the skin to heal and the resulting effects last longer when using topical treatments. The procedure is beneficial for some patients and can be recommended by dermatologists and cosmetics professionals. 

Laser and Light Treatment for Melasma 

Laser and light therapy are two methods that can help diminish melasma spots, but as with most treatments, it is important to proceed with caution and take into account the potential variations in results. 

Q-Switched Nd:YAG Laser

This laser sends fast pulses of energy into the skin that destroys melanin, which is absorbed to reduce spots on the skin. Due to its potential to cause recurrence upon multiple treatments it is often used sparingly. 

Picosecond Laser

The laser is designed to remove the pigment without causing any heat damage, using ultra-short pulses of light. In some instances the laser could be beneficial for the treatment of melasma. 

Fractional Laser

The work of the fractional laser is based on creating small injuries in the skin which stimulate skin renewal. It has a particular range of parameters to prevent pigmentation. 

Intense Pulsed Light

The use of IPL for the treatment of veins and unwanted pigment. It is ineffective on all skin types, but may be beneficial to some patients. 

Why Laser Can Worsen Melasma

When exposed to extremes of heat or to laser energy, melanocytes can be stimulated and their pigments increased. 

Is Laser or Cream Better for Melasma?

Sun protection and topical treatments are the staple of care, but lasers may be indicated in certain patients in the care of a dermatologist. 

Why Sun and Visible-Light Protection Matter 

Sunscreen and shade from the sun are important for melasma to avoid harmful exposure to ultraviolet (UV) radiation and visible light as exposure can trigger melanogenesis leading to worsening dark spots and risk of melasma recurrence. 

Daily Sunscreen

Sun exposure can cause new spots to form, so a broad spectrum, high SPF 30 or more, should be applied every morning to help minimize new spot formation and damage to the skin from the sun’s UV rays. 

Tinted Sunscreen

Sunscreen that contains tint may have an extra edge in blocking visible light that can cause melasma. Iron oxide is included in these sunscreens for its ability to block visible light. 

Hats and Shade

Shade and wide brimmed hats can help reduce the amount of sunlight exposure. 

Window and Driving Exposure

When driving or in the presence of glass, wear sunscreen as it can act as a window to UV rays. 

Heat Avoidance

Exposure to extreme heat may be a way of reducing the need for pigment stimulation. 

Gentle Skincare

It is important to use mild skin care products as melasma can be irritated and inflamed. 

When Will Results Be Visible?

The making of the pigment is slow and consequently the treatment for melasma is slow. Most patients will see improvements after weeks instead of months when treatment is well maintained. Individual response and the state of the skin is an important factor, along with the method of removal. However, in most cases, the use of sunscreens and special creams as recommended by dermatologists is necessary. 

Can Melasma Be Permanently Cured?

Melasma is a chronic condition and there is no definite means of cure. Improper treatment, however, and exposure to the sun can make it difficult to manage successfully. Long term prevention strategies must be followed as many factors can trigger or exacerbate the condition, to help achieve clear skin. 

Risks and Possible Side Effects 

Most treatments for melasma are relatively safe, but there are some side effects if not used properly, or without the supervision of a healthcare provider. 

Irritation and Redness

Topical medications and treatments can cause redness, itchiness, or inflammation to the skin.

Dryness and Peeling

Retinoids, acids, and other skin treatments or procedures (e.g., exfoliation) can cause peeling, dryness, and irritation.

Post-Inflammatory Hyperpigmentation

Hyperpigmentation following inflammation can happen on dark skin when using harsh or irritating treatments. 

Rebound Melasma

Skin can re pigment if treatment is discontinued or if the causes of the pigmentation are not controlled.

Exogenous Ochronosis

Sometimes, skin darkens into patches when treated with hydroquinone for a long time.

Steroid-Related Skin Thinning

Lotions with steroids may cause the skin to thin and weaken over time.

Blood-Clotting Risk With Oral Tranexamic Acid

Oral tranexamic acid has been reported to cause blood clots and should only be used following a medical examination.

Burns and Scarring From Procedures

Burns, scars or uneven pigmentation can occur as a result of burns or inappropriate laser parameters during the treatment. 

Melasma vs Post-Inflammatory Hyperpigmentation

There is a difference between the two. Melasma may be caused by hormonal fluctuations or by sun exposure and are characterized by symmetrical brown or grey patches. Meanwhile, PIH in the area develops after inflammation caused by acne or surgery.

Melasma vs Sun Spots

The causes of sun spots and melasma are different. Sun spots are tiny brown patches due to sun damage while Melasma is a condition which is affected by sun and hormones. 

How to Choose a Melasma Clinic in Islamabad

Choosing the best Islamabad melasma clinic is based on the dermatologist’s expertise, credentials, and experience. The most advanced melasma clinic will have advanced options, customized treatments, accurate evaluation and information regarding the risks and expected outcomes of the therapy. 

Melasma Treatment Cost in Islamabad 

Melasma treatment in Islamabad cost ranges from PKR 15000 to as high as PKR 120000. There are a number of factors that will determine the price of melasma treatment in Islamabad, including the treatment procedure, the number of sittings required, the darkness level of the melasma, and your individual needs. 

Frequently Asked Questions

What is melasma?

Due to the increased amount of melanin, a brown or gray-brown discolored patch of skin is formed on the face, which is a common skin condition known as melasma. 

What causes melasma on the face?

Melasma can be caused by sunlight, visible light, hormonal changes, genetic predispositions, heat and some medications. 

Is melasma caused by hormones?

In fact, a number of hormonal changes can induce pigment to form. 

Can pregnancy cause melasma?

Yes, pregnancy can trigger melasma, or the mask of pregnancy. 

Is melasma permanent?

Although it cannot be completely cured, melasma can be controlled, but if care is not taken, it may come back. 

Can melasma be cured completely?

While there are effective treatments for melasma that can help to fade pigmentation, there is no cure.

Which cream is best for melasma?

Your doctor may recommend one or a combination of  medications like hydroquinone, retinoids, azelaic acid.

Is hydroquinone safe for melasma?

When used in the right concentration and under the supervision of a dermatologist, hydroquinone is a safe and effective treatment for melasma. 

What is triple-combination cream?

This triple combination cream is a mix of hydroquinone, a retinoid, and a corticosteroid, that helps to lighten the skin.

Can tranexamic acid treat melasma?

Tranexamic acid may be beneficial in the treatment of this type of melasma, as decided by a physician.

Can melasma return after treatment?

It can come back if you do not protect yourself from the sun. 

Is melasma the same as hyperpigmentation?

Melasma is a form of hyperpigmentation that looks and causes differently. 

Can chemical peels improve melasma?

Some pigmentations can be improved with a superficial peel. 

Is melasma treatment safe during pregnancy?

The doctor should only give these if they are deemed safe for use during pregnancy. 

What sunscreen is best for melasma?

It is advised to wear a broad spectrum sunscreen with SPF 30 or higher, the ideal one is a color iron oxide.

How much does melasma treatment cost in Islamabad?

Melasma treatment in Islamabad cost ranges from PKR 15000 to as high as PKR 120000.

Why Choose Your Clinic?

Capella Esthetic treats melasma safely and effectively. Highly qualified specialists and thorough personal care ensure that this clinic is sure to keep your skin in good shape, and make it beautiful and flawless without leaving any marks. 

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